The human desire to give a shit is not defeatable.

from Craig Mazin and John August’s podcast (Mike is guest Mike Birbiglia):

Craig: You’ve lost your defenses and you’re expecting to laugh again. So, nobody sees it coming, you know? I remember talking to David Zucker and Jerry Zucker about the first time they screened the movie Airplane! for a test audience. And in their minds everything was jokes. They were just obsessed with how the jokes would play. And they were just thrown on their heels when at the end of the movie the plan finally lands and the audience bursts into applause.

Mike: Oh, that’s amazing.

Craig: Because they cared that the plane would land. You know? And they just thought, “It doesn’t matter. We’ve told them in every possible way this is not a real plane.” It is to them. It matters. And so the human desire to give a shit is not defeatable.